Keynote and Symposia Speakers

Keynote Lecture

Saturday, December 8, 6:00 pm

Niches for stem cells in bone marrow. Sean J Morrison, Children’s Medical Center Research Institute, UT Southwestern/HHMI

 Symposium 1: Nuclear Organization

Sunday, December 9, 8:00 am

	Super-resolution imaging of transcription in living mammalian cells. Ibrahim I. Cissé, Massachusetts Institute of Technology
	Genome Architecture Mapping: discovering 3D chromatin contacts in rare cell types. Ana Pombo, Berlin Institute for Medical Systems Biology
	Mechanisms of Transcriptional Bursting. Arjun Raj, University of Pennsylvania

 Symposium 2: Cell Migration

Sunday, December 9, 9:45 am

	Imaging leukocyte dynamics in vivo. Anna Huttenlocher, University of Wisconsin–Madison
	Principles of leukocyte locomotion and navigation. Michael Sixt, IST Austria

 Symposium 3: Neuronal Cell Biology

Sunday, December 9, 9:45 am

	Dynamics of autophagy in neuronal homeostasis and neurodegeneration. Erika Holzbaur, University of Pennsylvania
	Disturbance of Phase Transitions in Neurological Disease. J. Paul Taylor, St. Jude Children’s Research Hospital/HHMI

 Symposium 4: Cytoskeletal Dynamics

Monday, December 10, 8:00 am
Supported by The Anatomical Record and The American Association of Anatomists

	Control of cell architecture by microtubule minus-end binding proteins. Anna Akhmanova, Utrecht Universit
	The dynein/dynactin complex and long distance transport.  Andrew Carter, MRC Lab Molecular Biology
	Multi-component mechanisms controlling actin dynamics. Bruce Goode, Brandeis University

 Symposium 5: Metabolism

Monday, December 10, 9:45 am

	Metabolic Transitions in Cancer: Lessons from Viral Infection. Heather Christofk, David Geffen School of Medicine at UCLA
	Mechanisms and Physiology of Lipid Storage in Lipid Droplets. Robert Farese, Jr., Harvard School of Public Health and Harvard Medical School

Symposium 6: Regeneration and Morphogenesis*

Monday, December 10, 9:45 am

	Stem Cell-Based Organoids as Avatars in Human Disease. Hans Clevers, Hubrecht Institute
	Building the mouse and human embryo in vivo and in vitro.  Magdelena Zernicka-Goetz, University of Cambridge

 Symposium 7: Organelle Communication

Tuesday, December 11, 8:00 am

	The role of ER membrane contact sites in lipid metabolism and organelle biogenesis.  Will Prinz, National Institute of Diabetes and Digestive and Kidney Diseases, NIH
	mTOR and Lysosomes in Growth Control. David Sabatini, Whitehead Institute for Biomedical Research, Broad Institute, and Massachusetts Institute of Technology/HHMI
	New insights into mitochondrial vesicle transport. Heidi McBride, McGill University

 Symposium 8: Quality Control

Wednesday, December 12, 11:20 am

	Defining translational stress using ribosome profiling.  Rachel Green, Johns Hopkins University School of Medicine
	Targeting the Cell’s Stress Pathways for Therapeutic Benefit. Peter Walter, University of California, San Francisco

* Heinz Herrmann Symposium. Heinz Herrmann was Professor Emeritus of Molecular and Cell Biology at the University of Connecticut. A symposium in his honor was endowed at the ASCB in 1990. A founder of the ASCB, Professor Herrmann was well known for his pioneering approach to research in developmental biology, which has led to over 100 publications. He also wrote two books—Cell Biology andFrom Biology to Sociopolitics.