Subgroup D

Subgroup D: Evolutionary Cell Biology

Saturday, December 8, 8:30 am-12:30 pm
Room: 28 E

Organizers: Holly V. Goodson, University of Notre Dame; and Margaret A. Titus, University of Minnesota

Evolutionary cell biology (ECB) encompasses research with two complementary goals: 1) using the perspectives and methods of evolutionary biology to gain insight into cell biological processes; and 2) studying the biology and diversity of cells to gain insight into the process of evolution. These goals are unified by the expectation that studying these questions in the context of cells the basic units of life—should illuminate fundamental principles of living systems. Talks in this session were chosen from abstracts submitted in response to a request sent to the ECB community. To build this community, we are compiling a list of ECB-related talks and posters to distribute at this session. To include yours in this list, please send your presentation information to the session organizers.


8:30 am                     Introduction. Holly V. Goodson, University of Notre Dame; Margaret A. Titus, University of Minnesota

8:35 am                     Conserved and divergent aspects of microtubule structure and dynamic instability. Sami Chaaban, McGill University, Montreal, Canada (Gary Brouhard Lab)

8:55 am                    How does a cell with no interphase microtubules build a mitotic spindle? Lillian Fritz-Laylin, University of Massachusetts Amherst, Amherst, MA

9:15 am                    Emerging mechanisms generating cytoskeletal complexity in the aggregatively multicellular Rhizarian amoeba Corallomyxa tenera. Sarah Guest, University of California Davis, Davis, CA (Scott Dawson Lab)

9:25 am                    Viral capsids traffic along tubulin filaments in Pseudomonas to reach the phage nucleus. Joseph Pogliano, University of California San Diego, San Diego, CA

9:45 am                   Break

10:05 am                 Organisation and evolution of the eukaryotic cell. Mark Field, University of Dundee, Dundee, Scotland

10:25 am                 Evolutionary origins of the nuclear pore complex and nucleus. Michael Rout, Rockefeller University, New York, NY

10:45 am                 The regulation of nuclear remodelling at mitotic exit. Gautam Dey, University College London, London, England (Buzz Baum Lab)

10:55 am                 Unraveling the origins of animal cell type differentiation. Sebastián R. Najle, Institute of Evolutionary Biology, Barcelona, Spain (Iñaki Ruiz-Trillo Lab)

11:05 am                 Break

11:25 am                 Evolutionary adaptation to replication stress reveals plasticity in DNA metabolism. Marco Fumasoni, Harvard University, Boston MA (Andrew Murray Lab)

11:35 am                 A tale of two actins: significant functional overlap of divergent actin isoforms in the unicellular green alga Chlamydomonas reinhardtii. Prachee Avasthi, University of Kansas Medical Center, Kansas City, KS

11:55 am                 The Hippo pathway, which regulates tissue size, is present in the closest unicellular relatives of animals. Jonathan Phillips, University of Texas Southwestern Medical Center, Dallas, TX (DJ Pan Lab)

12:05 pm                 Evolution and engineering of allosteric regulation in protein kinases. Kimberly Reynolds, University of Texas Southwestern Medical Center, Dallas, TX

12:25 pm                Closing remarks. Holly Goodson and Margaret Titus


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