Subgroup B

Subgroup B: Building the Cell 2018

Saturday, December 8, 8:30 am-12:30 pm
Room: 30D

Organizer: Susanne Rafelski, Allen Institute for Cell Science, Seattle WA

Modern cell biology has made great strides in understanding cell structure and function. As with any engineering problem, however, there is a third important aspect that needs to be understood besides structure and function, and that is assembly. How are the complex three-dimensional structures found within the cell specified by a one-dimensional genome? In this session we will explore the mechanisms by which cellular structures are determined and regulated. Because this question lies at the interface of biology and physics, this Building the Cell session will be highly interdisciplinary with speakers whose interests range from physics and mathematical modeling to biochemistry and cell biology.

Presentations:

8:30 am          Introduction. Susanne Rafelski, Allen Institute for Cell Science

8:40 am          Creating a stem cell state landscape: integrated cellular reorganization during differentiation and division of the human iPS cell. Susanne Rafelski, Allen Institute for Cell Science

9:00 am          TBD – topic: building artificial membranes. Neal Devaraj, UC San Diego

9:20 am          Understanding the heterotypic mitochondrial outer membrane fusion machine. Suzanne Hoppins, University of Washington

9:40 am          The morphology space of yeast mitochondrial networks. Greyson Lewis, Wallace Marshall Lab, UC San Francisco

10:00 am        Harnessing motors, flows, and fluctuations for intracellular transport. Elena Koslover, UC San Diego

10:20 am        Break

10:40 am        A fundamental trade-off between information flow in single cells and cellular populations. Eric J. Deeds, University of Kansas

11:00 am        Dynamic architecture of the microtubule cytoskeleton. Marija Zanic, Vanderbilt University

11:20 am        Super-resolution imaging of chromatin organization. Melike Lakadamyali, University of Pennsylvania

11:40 am        Spreading of epigenetic silencing and activation in single cells. Lacramioara Bintu, Stanford University

12:00 pm        Design principles for self-organized cell polarity. Ed Munro, University of Chicago

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