Minisymposium 16

Organelle Homeostasis

Tuesday, December 11
4:15-6:50 pm
Room 30C
Co-Chairs: Adam Hughes, University of Utah School of Medicine; and Marisa Otegui, University of Wisconsin-Madison

4:15 pm       Introduction

4:20 pm   M159    Systematic superresolution analysis of endocytosis reveals an actin nucleation nano-template that drives efficient vesicle formation.  M. Mund^1,2, J. Beek¹, J. Deschamps¹, S. Dmitrieff¹, P. Hoess¹, J. Monster¹, A. Picco², F.J. Nedelec¹, M. Kaksonen², J. Ries¹; ¹Cell Biology and Biophysics, European Molecular Biology Laboratory, Heidelberg, Germany, ²Department of Biochemistry, University of Geneva, Geneva, Switzerland

4:35 pm   M160    Actin-independent endocytosis in yeast revealed through visualization of intracellular sterols with a bacterial toxin bio-sensor.  M. Marek¹, S.G. Martin¹; ¹Department of Fundamental Microbiology, University of Lausanne, Lausanne, Switzerland

4:50 pm   M161    FERARI: an unusual tether involved in endocytic recycling.  J.A. Solinger¹, H. Rashid¹, A. Spang¹; ¹Biozentrum, University of Basel, Basel, Switzerland

5:05 pm   M162    Architecture of mammalian retromer by single particle cryo-EM.  A.K. Kendall¹, B. Xie^1,2, C. Jung¹, E. Binshtein¹, S.E. Collier¹, P. Xu¹, R. Burcham¹, T. Graham¹, T. Nakagawa¹, L.P. Jackson¹;
¹Biological Sciences, Vanderbilt University, Nashville, TN, ²Center for Structural Biology, Vanderbilt University, Nashville, TN

*5:20 pm   M163    Catalytic activation of β-arrestins by GPCRs promotes independent β-arrestin trafficking and signaling.  K. Eichel¹, D. Jullié¹, B. Barsi-Rhyne¹, N. Latorraca², M. Masureel², J. Sibarita³, R. Dror², M. von Zastrow¹; ¹Psychiatry, University of California San Francisco, San Francisco, CA, ²Molecular and Cellular Physiology, Stanford University, Stanford, CA, ³Interdisciplinary Institute for Neuroscience, Bordeaux, France

5:35 pm   M164    Mechanism of miRNA sorting into extracellular vesicles.  M.M. Temoche-Diaz¹, M.J. Shurtleff^1,2, R. Nottingham³, J. Yao³, A. Lambowitz³, R.W. Schekman²; ¹Plant and Microbial Biology, University of California, Berkeley, Berkeley, CA, ²Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA, ³Institute for Cellular and Molecular Biology, University of Texas at Austin, Austin, TX

5:50 pm   M165    Mitochondrial-Derived Compartments Promote Nutrient-Dependent Remodeling of the Mitochondrial Proteome.  M. Schuler¹, A.M. Litwiller¹, T.J. Campbell¹, T. Tedeschi¹, J.M. Shaw¹, A.L. Hughes¹; ¹Biochemistry, University of Utah, Salt Lake City, UT

6:05 pm   M166    The triggering of a spatially segregated ESCRT-nuclear envelope repair system leads to local nuclear membrane remodeling.  D.J. Thaller¹, M. Allegretti², S. Borah¹, M. Beck², P. Lusk¹; ¹Cell Biology, Yale School of Medicine, New Haven, CT, ²EMBL, Heidelberg, Germany

6:20 pm   M167    Lipid homeostasis is maintained by dual targeting of the mitochondrial PE biosynthesis enzyme Psd1 to the ER.  J.R. Friedman^1,2, M. Kannan³, A. Toulmay³, C.H. Jan^4,5, W. Prinz³, J.S. Weissman⁴, J. Nunnari²; ¹Cell Biology, UT Southwestern Medical Center, Dallas, TX, ²Molecular and Cellular Biology, University of California Davis, Davis, CA, ³NIDDK, NIH, Bethesda, MD, ⁴Department of Cellular and Molecular Pharmacology, UCSF, San Francisco, CA, ⁵Calico Life Sciences, South San Francisco, CA

6:35 pm   M168    Reticulon proteins in plants: Membrane remodeling and autophagy.  X. Zhang¹, X. Ding¹, R. Marshall², R.D. Vierstra², M.S. Otegui¹; ¹Laboratory of Cell and Molecular Biology, University of Wisconsin-Madison, Madison, WI, ²Biology, Washington University at St Louis, St Louis, MO

* Kelsie Eichel is the 2018 ASCB Merton Bernfield Awardee.

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