Cell Size, Cell Division, and Contractility
Tuesday, December 11
Co-Chairs: Jan Skotheim, Stanford University; and Amy Maddox, University of North Carolina – Chapel Hill
4:15 pm Introduction
4:20 pm M139 Constructing DNA-binding modules to sense changes in cell volume. C.W. Sandlin1, H. Chen1, M.C. Good1; 1Cell and Developmental Biology, University of Pennsylvania, Philadelphia, PA
4:35 pm M140 The biosynthetic basis of cell size control. D. Chandler-Brown1, K. Schmoller1, M. Swaffer1, J. Turner1, M. Langhinrichs1, J.M. Skotheim1; 1Biology, Stanford University, Stanford, CA
4:50 pm M141 Aurora-A breaks symmetry in C. elegans zygotes independently of its role in centrosome maturation. P. Zhao1,2, X. Teng3, M. Nishikawa4, Y. Toyama2,3, F. Motegi1,2,3; 1Temasek Lifesciences Laboratory, Singapore, Singapore, 2Biological Sciences, National University of Singapore, Singapore, Singapore, 3Mechanobiology Institute, Singapore, Singapore, 4Frontier Bioscience, Hosei University, Tokyo, Japan
5:05 pm M142 A reaction-diffusion mechanism for crossover regulation during meiosis. L. Zhang1,2, W.T. Stauffer2,3, S. Köhler1,2, R. Rillo-Bohn1,2, A.F. Dernburg1,2,4,5; 1Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA, 2Howard Hughes Medical Institute, Chevy Chase, MD, 3Integrative Biology, University of California, Berkeley, Berkeley, CA, 4California Institute for Quantitative Biology (QB3), Berkeley, CA, 5Biological Systems and Engineering, Lawrence Berkeley National Laboratory, Berkeley, CA
5:20 pm M143 The regulation of nuclear remodelling at mitotic exit. G. Dey1, S. Bruderer1,2, M. Balasubramanian3, W. Kukulski4, B. Baum1; 1MRC Lab for Molecular Cell Biology, University College London, London, United Kingdom, 2Imperial College London, London, United Kingdom, 3Warwick Medical School, University of Warwick, Warwick, United Kingdom, 4MRC Lab for Molecular Biology, Cambridge, United Kingdom
*5:35 pm M144 Metaphase actin waves drive mitochondrial motility to promote spatial mixing of mtDNA before cell division. A.S. Moore1, S.M. Coscia1, C.L. Simpson1, J.J. Nirschl1, E.L. Holzbaur1; 1Physiology, University of Pennsylvania, Philadelphia, PA
5:50 pm M145 Integration of biochemical signals and mechanical forces in the synchronization of the cell cycle. V.E. Deneke1, A. Puliafito2, D. Krueger3, A. Narla4, M. Vergassola4, S. De Renzis3, S. Di Talia1; 1Cell Biology, Duke University, Durham, NC, 2IRCC, Turin, Italy, 3EMBL Heidelberg, Heidelberg, Germany, 4University of California San Diego, San Diego, CA
6:05 pm M146 Three mechanisms generate tension in the fission yeast contractile ring: sliding filament, fixed filament and unanchored myosin-II. S. Thiyagarajan1, S. Wang2, H.F. Chin1, T.D. Pollard3,4,5, B. O’Shaughnessy1; 1Chemical Engineering, Columbia University, New York, NY, 2Physics, Columbia University, New York, NY, 3Molecular Cellular and Developmental Biology, Yale University, New Haven, CT, 4Molecular Biophysics and Biochemistry, Yale University, New Haven, CT, 5Cell Biology, Yale University, New Haven, CT
6:20 pm M147 Actin filaments locally template filament elongation to provide a structural memory of filament alignment during cytokinesis. Y. Li1, E.M. Munro1,2; 1Committee on Development, Regeneration, and Stem Cell Biology, the University of Chicago, Chicago, IL, 2Molecular Genetics and Cell Biology, the University of Chicago, Chicago, IL
6:35 pm M148 Novel cytokinetic ring components limit myosin levels and closure speed. K.R. Bell1, M.E. Werner1, A. Doshi1, D.B. Cortes1, A.S. Maddox1; 1Biology, UNC – Chapel Hill, Chapel Hill, NC
* Andrew Moore is an ASCB Porter Prize for Research Excellence Awardee.
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