Minisymposium 13

Cell Biology of the Neuron

Supported by The Kavli Foundation

Tuesday, December 11
4:15-6:50 pm
Room 28C
Co-Chairs: Brenda Bloodgood, University of California, San Diego; and Gentry Patrick, University of California, San Diego

4:15 pm       Introduction

4:20 pm   M129    Mitochondria tune neuronal computation in the Drosophila visual system.  E.L. Barnhart1,2, C. Desplan2, T.R. Clandinin1; 1Neurobiology, Stanford, Stanford, CA, 2Biology, NYU, New York, NY

4:35 pm   M130    Activity-dependent trafficking and function of lysosomes in dendrites and dendritic spines.  M. Goo1, L. Sancho1, N. Slepak1, S.K. Gilmore1, D. Boassa2, T.J. Deerinck2, M.H. Ellisman2,3,4, B.L. Bloodgood1, G.N. Patrick1; 1Section of Neurobiology, Division of Biological Sciences, University of California, San Diego, La Jolla, CA, 2National Center for Microscopy, and Imaging Research and Center for Research on Biological Systems, La Jolla, CA, 3Department of Neurosciences, University of California, San Diego, La Jolla, CA, 4Salk Institute for Biological Studies, San Diego, CA

4:50 pm   M131    Phosphofructokinase (PFK-1) self-interaction is necessary for its clustering near synapses.  Z. Xuan1, S.K. Jang1, S. Prashad1, L. Jawerth2, B. Kim1, A. Patel2, D. Albrecht3, A.A. Hyman2, D.A. Colón-Ramos1,4; 1Department of Neuroscience, Cell Biology and Program in Cellular Neuroscience, Neurodegeneration and Repair, Yale University, New Haven, CT, 2Max Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany, 3Department of Biomedical Engineering, Worcester Polytechnic Institute, Worcester, MA, 4Instituto de Neurobiología, Universidad de Puerto Rico, San Juan, Puerto Rico

5:05 pm   M132    ATP-dependent phase transition of peri-active zone and active zone bio-condensates regulate synapse organization and function.  L. Guillaud1, T. Takahashi1; 1Cellular and Molecular Synaptic Function, Okinawa Institute of Science and Technology, Onna-Son, Okinawa, Japan

5:20 pm   M133    Axon injury triggers a liquid-solid transition of an intrinsic inhibitor of regeneration.  M.G. Andrusiak1, P. Sharifnia1, Z. Wang1, Z. Wu1, A.M. Dickey1, A.D. Chisholm1, Y. Jin1;
1Biological Sciences, University of California, San Diego, La Jolla, CA

5:35 pm   M134    Microcephaly mutations disrupt chromosome integrity in neurons.  A.T. Kodani1,2, P. Li1, C. Kenny1, C.A. Walsh1,2, R. Rodin1; 1Genetics and Genomics, Boston Children’s Hospital, Boston, MA, 2Pediatrics, Harvard Medical School, Boston, MA

5:50 pm   M135    TorsinA and Neuronal Nuclear Pore Complex Biogenesis.  S. Kim1, S.S. Pappas2, W.T. Dauer1,2,3; 1Cellular and Molecular Biology Graduate Program, University of Michigan, Ann Arbor, MI, 2Department of Neurology, University of Michigan, Ann Arbor, MI, 3Department of Cell & Developmental Biology, University of Michigan, Ann Arbor, MI

6:05 pm   M136    Communication of pathway-specific circuit activity to the genome by the immediate early gene transcription factor NPAS4.  G. Brigidi1, M. Hayes2, P. Lin3, A. Hartzell3, S. Heinz2, B.L. Bloodgood1; 1Division of Biological Sciences, University of California, San Diego, La Jolla, CA, 2Medicine, University of California, San Diego, La Jolla, CA, 3Neurosciences Graduate Program, University of California, San Diego, La Jolla, CA

6:20 pm   M137    Viral-like mechanisms of intercellular RNA trafficking in the nervous system.  E. Pastuzyn1, R. Kearns1, J. Einstein1, J. Shepherd1; 1Neurobiology and Anatomy, University of Utah, Salt Lake City, UT

6:35 pm   M138    Rab11 and Retromer act antagonistically to one another to regulate neuronal extracellular vesicle cargo.  R.B. Walsh1, M.A. Zunitch1, A.N. Becalska1, A. Yeh1, H. Ye2,3, J. Shulman2,3, A.A. Rodal1; 1Biology, Brandeis University, Waltham, MA, 2Neurology, Neuroscience, and Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, 3Jan and Dan Duncan Neurological Research Institute, Texas Children’s Hospital, Houston, TX

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