Minisymposium 12

Biomechanics

Tuesday, December 11
4:15-6:50 pm
Room 29C
Co-Chairs: Katja Röper, MRC Laboratory of Molecular Biology; and Michel Labouesse, Institute of Biology Paris – Seine

4:15 pm       Introduction

4:20 pm   M119    Epithelial tissue fracture dynamics govern fast and extreme plastic shape changes in Trichoplax adhaerens.  V.N. Prakash¹, M.S. Bull², M. Prakash¹; ¹Department of Bioengineering, Stanford University, Stanford, CA, ²Department of Applied Physics, Stanford University, Stanford, CA

4:35 pm   M120    Extrinsic stress triggers actin-based viscoplasticity in a ratchet-based morphogenetic process.  A. Lardennois¹, G. Pasti¹, X. Yang^1,2, T. Ferraro¹, J. Pontabry², F. Llense¹, D. Rodriguez², C. Gally¹, M. Labouesse^1,2; ¹Laboratoire de Biologie du Développement, Institut de Biologie Paris-Seine, Paris, France, ²Institut de Génétique Biologie Moléculaire et Cellulaire, Strasbourg, France

4:50 pm   M121    Asymmetric biogenesis of occluding junctions drives integration of stem cell progeny during epithelial turnover.  P. Moreno-Roman¹, I. Kolotueva², B. Humbel², L.E. O’Brien³; ¹Department of Biology, Stanford University, Stanford, CA, ²Electron Microscopy Facility, Université de Lausanne, Lausanne, Switzerland, ³Department of Molecular and Cellular Physiology, Stanford University, Stanford, CA

5:05 pm   M122    Radially-patterned cell behaviours during tube budding from an epithelium.  K. Röper¹, Y.E. Sanchez Corrales¹, G.B. Blanchard²; ¹Cell Biology, MRC-Laboratory of Molecular Biology, Cambridge, United Kingdom, ²Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, United Kingdom

5:20 pm   M123    3D Tissue elongation via ECM stiffness-cued junctional remodeling.  D. Chen¹, J. Crest¹, S.J. Streichan², D. Bilder¹; ¹Dept. of Molecular & Cell Biology, University of California, Berkeley, Berkeley, CA, ²Dept. of Physics, University of California, Santa Barbara, Santa Barbara, CA

5:35 pm   M124    Differential expression of Cadherin-2 patterns RhoA and Myosin activity to drive zippering and neural tube closure in a simple chordate.  H. Hashimoto¹, E.M. Munro^1,2; ¹Department of Molecular Genetics and Cell Biology, University of Chicago, Chicago, IL, ²Committee on Development, Regeneration and Stem Cell Biology, University of Chicago, Chicago, IL

5:50 pm   M125    Structural redundancy in supracellular actomyosin network connections enables robust tissue folding.  H.G. Yevick¹, A.C. Martin¹; ¹Biology, MIT, Cambridge, MA

6:05 pm   M126    The Diaphanous-Related Formin, Dia1, Acts Upon Cell Junctions to Coordinate Differentiation and Cell Sorting in a Stratified Epithelium.  R.M. Harmon¹, M.L. Gardel¹; ¹Institute of Biophysical Dynamics, University of Chicago, Chicago, IL

6:20 pm   M127    Mechanical signaling underlies self-organized regions of mesoderm differentiation in hESC colonies.  N.M. Ayad^1,2, J.M. Muncie^1,2, L. Przybyla², J.N. Lakins², R. Sunyer³, X. Trepat³, V.M. Weaver^1,2,4; ¹Graduate Program in Bioengineering, UC Berkeley – UCSF, San Francisco, CA, ²Center for Bioengineering and Tissue Regeneration, Department of Surgery, University of California San Francisco, San Francisco, CA, ³Institute for Bioengineering of Catelonia (IBEC), Universitat de Barcelona, Barcelona, Spain, ⁴Department of Anatomy, Department of Bioengineering and Therapeutic Sciences, Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research, Helen Diller Family Comprehensive Cancer Center, University of California San Francisco, San Francisco, CA

6:35 pm   M128    Lateral inhibition in cell fate specification is mediated by mechanical signals modulating TAZ activity.  P. Xia¹, D. Gütl¹, V. Zheden¹, C. Heisenberg¹; ¹IST AUSTRIA, Klosterneuburg, Austria

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