Minisymposium 10

Phase Transitions in the Cell

Monday, December 10
4:30-7:05 pm
Room 28C
Co-Chairs: Amy Gladfelter, University of North Carolina at Chapel Hill; and D. Allan Drummond, The University of Chicago

4:30 pm       Introduction

4:35 pm   M99    Poly-Q dependent phase separations drive spatial heterogeneity in cytoplasmic crowding.  E.M. Langdon1, J. Newby2, G. McLaughlin1, T.M. Gerbich1, M. Roper3, L. Holt4, A.S. Gladfelter1; 1Biology, University of North Carolina, Chapel Hill, NC, 2Mathematics, University of North Carolina, Chapel Hill, NC, 3Mathematics, University of California, Los Angeles, CA, 4Biochemistry, New York University School Of Medicine, New York City, NY

4:50 pm   M100    Stress-sensitive phase separation regulates translation of stress-induced mRNAs.  C.D. Katanski1, H. Yoo1, C. Iserman2, E. Pilipenko1, S. Alberti2, D.A. Drummond1; 1Biochemistry and Molecular Biology, University of Chicago, Chicago, IL, 2Max Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany

5:05 pm   M101   Phase separation potentiates the condensation of mitochondrial nucleoids in a premature aging disease. M. Feric1, T. Misteli2; 1National Institute of General Medical Sciences, National Institutes of Health, Bethesda, MD, 2National Cancer Institute, National Institutes of Health, Bethesda, MD

5:20 pm   M102    Phase transition drives telomere clustering.  H. Zhang1, M. Liu1, C. Aonbangkhen2, R. Dilley3,4, R.A. Greenberg3,4, D.M. Chenoweth2, M.A. Lampson1; 1Biology, University of Pennsylvania, Philadelphia, PA, 2Chemistry, University of Pennsylvania, Philadelphia, PA, 3Cancer Biology, University of Pennsylvania, Philadelphia, PA, 4 Pathology, University of Pennsylvania, Philadelphia, PA

5:35 pm   M103    Stoichiometry controls activity of phase separated clusters of actin signaling proteins.  L.B. Case1, X. Zhang1, J.A. Ditlev1, M.K. Rosen1; 1Department of Biophysics, UT Southwestern Medical Center, Dallas, TX

5:50 pm   M104    Synthetic condensed-phase signaling.  D. Sang1, A. Rice2, M.K. Rosen2, L.J. Holt1; 1Institute for Systems Genetics, New York University, New York, NY, 2Department of Biophysics, University of Texas Southwestern, Dallas, TX

6:05 pm   M105    The liquid core of P granules is stabilized by a gel-like shell.  A. Putnam1,2, M. Cassani1,2, G. Seydoux1,2; 1Molecular Biology and Genetics, Johns Hopkins School of Medicine, Baltimore, MD, 2Howard Hughes Medical Institute, Baltimore, MD

6:20 pm   M106    The Balbiani Body and how it disassembles.  C. Martinez-Guillamon1, E. Boke1,2; 1Cell and Developmental Biology, Centre for Genomic Regulation (CRG), Barcelona, Spain, 2Universitat Pompeu Fabra (UPF), Barcelona, Spain

6:35 pm   M107    Age-induced large and stable P-bodies predict the future lifespan of yeast.  J. Choi1, S. Wang1, B.M. Zid1; 1The Department of Chemistry and Biochemistry, The University of California, San Diego, La Jolla, CA

6:50 pm   M108    Multiple cellular mechanisms maintain the liquidity of an RNA-protein condensate, stress granules.  H.O. Lee1, A. Schwager2, S. Spannl1, A.A. Hyman2; 1Biochemistry, University of Toronto, Toronto, ON, 2Max Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany

Click here to return to full list of Minisymposia.