Minisymposium 1

Biology of Stem Cells

Sunday, December 9
4:15 pm-6:50 pm
Room 29C
Co-Chairs: David Traver, University of California, San Diego; and Ruwanthi Gunawardane, Allen Institute for Cell Science

4:15 pm       Introduction

4:20 pm   M1    Creating a stem cell state map of hiPSCs from pluripotency through cardiomyocyte differentiation.  R. Gunawardane1; 1Allen Institute for Cell Science, Seattle, WA

4:35 pm   M2    A mechanism for Wnt-Fzd specificity in hematopoietic development.  S. Grainger1, N. Nguyen1, J. Richter1, J. Setayesh1, B. Lonquich1, C. Oon1, J.M. Wozniak2, R. Barahona1, C.N. Camei3, I.A. Drummond3,4, D. Gonzalez2, K. Willert1, D. Traver1; 1Cellular and Molecular Medicine, University of California San Diego, La Jolla, CA, 2Department of Pharmacology, University of California San Diego, La Jolla, CA, 3Nephrology, Massachusetts General Hospital , Charlestown, MA, 4Genetics, Harvard Medical School, Boston, MA

4:50 pm   M3    Beyond Goosebumps: Interactions between the hair follicle, the arrector pili muscle, and the sympathetic nerve during development and hair follicle regeneration.  Y. Shwartz1, M. Gonzalez Celeiro1, J. Chen2, S. Lin2, Y. Hsu1; 1Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA, 2Institute of Biomedical Engineering, National Taiwan University, Taipei, Taiwan

5:05 pm   M4    JNK-mediated spindle reorientation in stem cells promotes loss of tissue homeostasis in the aging intestinal epithelium.  D.J. Hu1, H. Jasper1,2; 1Immunology Discovery, Genentech, South San Francisco, CA, 2Buck Institute of Research for Aging, Novato, CA

5:20 pm   M5    Pannexin 1 regulates skeletal muscle regeneration by promoting bleb-based myoblast migration and fusion through a novel lipid based signaling mechanism.  T. Zyrianova1, T. Zyrianova2, H. Collins-Hooper3, A. Gromova1, R. Meech4, A. Sacco5, P.R. Dash3, R. Mitchell3, V. Shestopalov6, T.E. Woolley7, K. Patel3, H.P. Makarenkova1; 1Molecular Medicine, The Scripps Research Institution, La Jolla, CA, 2BioScience Center, San Diego State University, San Diego, CA, 3School of Biological Sciences, University of Reading, Berkshire, United Kingdom, 4Department of Clinical Pharmacology, Flinders University, South Australia, Australia, 5Sanford Children’s Health Research Center, Sanford-Burnham Medical Research Institute, La Jolla, CA, 6Bascom Palmer Eye Institute, University of Miami School of Medicine, Miami, FL, 7Mathematical Institute, University of Oxford, Oxford, United Kingdom

5:35 pm   M6    Signaling dynamics control cell fate in the early Drosophila embryo.  H.E. Johnson1, S.Y. Shvartsman2,3, J.E. Toettcher1; 1Molecular Biology, Princeton University, Princeton, NJ, 2Chemical Engineering, Princeton University, Princeton, NJ, 3Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, NJ

5:50 pm   M7    The SCRIB paralog Lano/LRRC1 regulates breast cancer stem cell fate through WNT/b-catenin signaling.  M. Sebbagh1, L. Lopez-Almeida1, F. Bertucci1, P. Finetti1, J. Wicinski1, S. Marchetto1, R. Castellano1, E. Josselin1, E. Charafe-JauffretT1, C. Ginestier1, J. Borg1, M. Santoni1; 1Institut Paoli-Calmettes, CRCM INSERM_CNRS_Aix Marseille Université, Marseille, France

6:05 pm   M8    Regulation of 4D nucleome during cell fate transition.  K. Shevade1, R. Bajpai1, J.A. Bernstein2; 1CCMB and Biochemistry, University of Southern California, Los Angeles, CA, 2Pediatrics, Stanford University, Palo Alto, CA

6:20 pm   M9    C. elegans DYNLL1/2 Ortholog Associates with RNP Complexes to Promote Germline mRNA Regulation.  N. Day1, M. Ellenbecker1, E. Voronina1; 1Division of Biological Sciences, University of Montana, Missoula, MT

6:35 pm   M10    Arp2/3 Complex Activity Times Stage Transition for Embryonic Stem Cell Differentiation.  F.M. Aloisio1, D.L. Barber1; 1Department of Cell & Tissue Biology, University of California, San Francisco, San Francisco, CA

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