Microsymposium 7

Advances in Mechanisms of Cellular Stress 

Monday, December 10
11:00 am-12:00 pm
Room 30B
Moderator: Arunika Das, University of Pennsylvania

11:00 am   E37    Temperature increases cause transposon-associated DNA damage specific to spermatocytes and not oocytes.  N.A. Kurhanewicz1, J.M. Helm1, D.E. Libuda1,2; Institute of Molecular Biology, University of Oregon, Eugene, OR, 2Department of Biology, University of Oregon, Eugene, OR

11:10 am   E38    Actin-mediated structural changes preserve neuron integrity in the early hours after experimental stroke.  B. Calabrese1,2, S.L. Jones3, U. Manor4, T.M. Svitkina3, H.N. Higgs5, A.Y. Shih6, S. Halpain1,2; 1Division of Biological Sciences, UC San Diego, La Jolla, CA, 2Sanford Consortium for Regenerative Medicine, UC  San Diego, La Jolla, CA, 3Departmen of Biology, University of Pennsylvania, Philadelphia, PA, 4Biophotonics Core Facility, Salk Institute, La Jolla, CA, 5Department of Biochemistry, Dartmouth Medical School, Hanover, NH, 6Department of Neurosciences, Medical University of South Carolina, Charleston, SC

11:20 am   E39    The Role of Sigma-1-Receptor in Endoplasmic Reticulum Stress and Alzheimer’s Disease.  T.T. Nguyen1,2, K.L. Ferguson2, P. Chudalayandi1,2, R. Bergeron1,2; 1Neuroscience, Ottawa Hospital Research Institute , Ottawa, ON, 2Cellular and Molecular Medicine, University of Ottawa, Ottawa, ON

11:30 am   E40    Enforcing cellular stress promotes apoptotic and immunogenic responses in melanoma.  S.M. Daignault1,2, L. Spoerri1,2, R.J. Ju1,2, D.S. Hill3,4, S.J. Stehbens1,2, R. Dolcetti1,2, N.K. Haass1,2,3,4;1Diamantina Institute, University of Queensland, Brisbane, Australia, 2Translational Research Institute, Woolloongabba, Australia, 3The Centenary Institute, Newtown, Australia, 4Dermatological Sciences, Newcastle University, Newcastle upon Tyne, United Kingdom

11:40 am   E41    Yeast tRNA ligase structure reveals kinetic competition between non-conventional mRNA splicing and mRNA decay.  J. Peschek1,2, P. Walter1,2; 1Biochemistry and Biophysics, UC San Francisco, San Francisco, CA, 2HHMI, Chevy Chase, MD

11:50 am   E42    Cell Stress Biosensors for Rapid, Live-Cell Detection of Neurotoxic and Cardiotoxic Compounds in iPSC-Derived Neurons and Cardiomyocytes.  K.M. Harlen1, T. Hughes1,2, A.M. Quinn1; 1Montana Molecular, Bozeman, MT, 2Cell Biology and Neuroscience, Montana State University, Bozeman, MT

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