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Microsymposium 7
Advances in Mechanisms of Cellular Stress
Monday, December 10
11:00 am-12:00 pm
Room 30B
Moderator: Arunika Das, University of Pennsylvania
11:00 am E37 Temperature increases cause transposon-associated DNA damage specific to spermatocytes and not oocytes. N.A. Kurhanewicz1, J.M. Helm1, D.E. Libuda1,2; Institute of Molecular Biology, University of Oregon, Eugene, OR, 2Department of Biology, University of Oregon, Eugene, OR
11:10 am E38 Actin-mediated structural changes preserve neuron integrity in the early hours after experimental stroke. B. Calabrese1,2, S.L. Jones3, U. Manor4, T.M. Svitkina3, H.N. Higgs5, A.Y. Shih6, S. Halpain1,2; 1Division of Biological Sciences, UC San Diego, La Jolla, CA, 2Sanford Consortium for Regenerative Medicine, UC San Diego, La Jolla, CA, 3Departmen of Biology, University of Pennsylvania, Philadelphia, PA, 4Biophotonics Core Facility, Salk Institute, La Jolla, CA, 5Department of Biochemistry, Dartmouth Medical School, Hanover, NH, 6Department of Neurosciences, Medical University of South Carolina, Charleston, SC
11:20 am E39 The Role of Sigma-1-Receptor in Endoplasmic Reticulum Stress and Alzheimer’s Disease. T.T. Nguyen1,2, K.L. Ferguson2, P. Chudalayandi1,2, R. Bergeron1,2; 1Neuroscience, Ottawa Hospital Research Institute , Ottawa, ON, 2Cellular and Molecular Medicine, University of Ottawa, Ottawa, ON
11:30 am E40 Enforcing cellular stress promotes apoptotic and immunogenic responses in melanoma. S.M. Daignault1,2, L. Spoerri1,2, R.J. Ju1,2, D.S. Hill3,4, S.J. Stehbens1,2, R. Dolcetti1,2, N.K. Haass1,2,3,4;1Diamantina Institute, University of Queensland, Brisbane, Australia, 2Translational Research Institute, Woolloongabba, Australia, 3The Centenary Institute, Newtown, Australia, 4Dermatological Sciences, Newcastle University, Newcastle upon Tyne, United Kingdom
11:40 am E41 Yeast tRNA ligase structure reveals kinetic competition between non-conventional mRNA splicing and mRNA decay. J. Peschek1,2, P. Walter1,2; 1Biochemistry and Biophysics, UC San Francisco, San Francisco, CA, 2HHMI, Chevy Chase, MD
11:50 am E42 Cell Stress Biosensors for Rapid, Live-Cell Detection of Neurotoxic and Cardiotoxic Compounds in iPSC-Derived Neurons and Cardiomyocytes. K.M. Harlen1, T. Hughes1,2, A.M. Quinn1; 1Montana Molecular, Bozeman, MT, 2Cell Biology and Neuroscience, Montana State University, Bozeman, MT
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(separate registration required)
Attend the 2018 Doorstep Meeting: Beyond Homeostasis: Stem Cells Under Stress on Saturday, December 8 from 8:00 am to 5:30 pm and attend the Keynote by Sean Morrison immediately following.
The daylong meeting will provide an overview of stem cell biology as it pertains to cell biology research and tissue regeneration, illustrate how studies of the cell provide insights into stem cell research, and encourage stem cell researchers to consider cell biology in their research. Click here for more information or to register. Meeting limited to 200 people.