Microsymposium 14

Motility

Tuesday, December 11
11:00 am-12:00 pm
Room 30C
Moderator: Krishnakumar Vasudevan, Stanford University

11:00 am   E79    Arp2/3-nucleated dendritic actin networks are required structures for adhesion formation and cell spreading in 3D.  T. Isogai^1,2, K.M. Dean^1,2, S.J. Han^1,2, P. Roudot^1,2, M.K. Driscoll^1,2, E.S. Welf^1,2, J.D. Cillay^1,2, K.A. Sochacki³, J.W. Taraska³, R. Fiolka², G. Danuser^1,2; ¹Lyda Hill Department of Bioinformatics, UT Southwestern Medical Center, Dallas, TX, ²Department of Cell Biology, UT Southwestern Medical Center, Dallas, TX, ³Laboratory of Molecular Biophysics, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD

11:10 am   E80    Macropinocytosis overcomes directional bias due to hydraulic resistance to enhance space exploration by dendritic cells.  H.D. Moreau¹, C. Blanch-Mercader², R. Attia^3,4, M. Maurin¹, Z. Alraies¹, D. Sanséau¹, O. Malbec¹, M. Delgado¹, P. Bousso^5,6, J. Joanny^2,7, R. Voituriez⁸, M. Piel^3,4, A. Lennon-Dumenil¹; ¹INSERM U932, Institut Curie, ANR-10-IDEX-0001-02 PSL* and ANR-11-LABX-0043, Paris, France, ²PSL Research University, Sorbonne Universités, UPMC – CNRS, Laboratoire PhysicoChimie Curie, Institut Curie , PARIS, France, ³Institut Curie, PSL Research University, CNRS, UMR 144, PARIS, France, ⁴Institut Pierre-Gilles de Gennes, PSL Research University, PARIS, France, ⁵Institut Pasteur, Dynamics of Immune Responses Unit, PARIS, France, ⁶INSERM U1223, PARIS, France, ⁷ESPCI Paris-Tech, PARIS, France, ⁸Laboratoire Jean Perrin, UM 8237 CNRS/UPMC, Paris, France

11:20 am   E81    Resolving the 3D nano-architecture of actin networks at the leading edge of cells.  J.A. Galbraith¹, J. Aaron², G. Shtengel², H. Hess², C.G. Galbraith¹; ¹Spatial Systems Biomedicine, Oregon Health Science University, Portland, OR, ²Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, VA

11:30 am   E82    A viral fusogen hijacks the actin cytoskeleton to drive cell-cell fusion.  K. Chan¹, S. Son², E.M. Schmid², D.A. Fletcher^1,2,3,4; ¹UC Berkeley/UC San Francisco Graduate Group in Bioengineering, Berkeley, CA, ²Department of Bioengineering, University of California, Berkeley, Berkeley, CA, ³Biophysics Program, University of California, Berkeley, Berkeley, CA, ⁴Physical Biosciences Division, Lawrence Berkeley National Laboratory, Berkeley, CA

11:40 am   E83    Firing of the harpoon-like invasion machinery of microsporidian parasites by high-speed microscopy.  P. Jaroenlak¹, M. Cammer², F. Liang², J.J. Becnel³, D.C. Ekiert¹, G. Bhabha¹; ¹Skirball Institute of Biomolecular Medicine, New York University School of Medicine, New York, NY, ²Microscopy Laboratory, New York University School of Medicine, New York, NY, ³Center for Medical, Agricultural, and Veterinary Entomology, Agricultural Research Service, US Department of Agriculture, Gainesville, FL

11:50 am   E84    Cell-extrinsic mechanical forces induce neutrophil polarization in the absence of leading-edge actin assembly pathways.  B.R. Graziano¹, A. Diz-Muñoz², O.D. Weiner¹; ¹Cardiovascular Research Institute, UCSF, San Francisco, CA, ²Cell Biology and Biophysics, EMBL, Heidelberg, Germany

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