Microsymposium 14

Motility

Tuesday, December 11
11:00 am-12:00 pm
Room 30C
Moderator: Krishnakumar Vasudevan, Stanford University

11:00 am   E79    Arp2/3-nucleated dendritic actin networks are required structures for adhesion formation and cell spreading in 3D.  T. Isogai1,2, K.M. Dean1,2, S.J. Han1,2, P. Roudot1,2, M.K. Driscoll1,2, E.S. Welf1,2, J.D. Cillay1,2, K.A. Sochacki3, J.W. Taraska3, R. Fiolka2, G. Danuser1,2; 1Lyda Hill Department of Bioinformatics, UT Southwestern Medical Center, Dallas, TX, 2Department of Cell Biology, UT Southwestern Medical Center, Dallas, TX, 3Laboratory of Molecular Biophysics, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD

11:10 am   E80    Macropinocytosis overcomes directional bias due to hydraulic resistance to enhance space exploration by dendritic cells.  H.D. Moreau1, C. Blanch-Mercader2, R. Attia3,4, M. Maurin1, Z. Alraies1, D. Sanséau1, O. Malbec1, M. Delgado1, P. Bousso5,6, J. Joanny2,7, R. Voituriez8, M. Piel3,4, A. Lennon-Dumenil1; 1INSERM U932, Institut Curie, ANR-10-IDEX-0001-02 PSL* and ANR-11-LABX-0043, Paris, France, 2PSL Research University, Sorbonne Universités, UPMC – CNRS, Laboratoire PhysicoChimie Curie, Institut Curie , PARIS, France, 3Institut Curie, PSL Research University, CNRS, UMR 144, PARIS, France, 4Institut Pierre-Gilles de Gennes, PSL Research University, PARIS, France, 5Institut Pasteur, Dynamics of Immune Responses Unit, PARIS, France, 6INSERM U1223, PARIS, France, 7ESPCI Paris-Tech, PARIS, France, 8Laboratoire Jean Perrin, UM 8237 CNRS/UPMC, Paris, France

11:20 am   E81    Resolving the 3D nano-architecture of actin networks at the leading edge of cells.  J.A. Galbraith1, J. Aaron2, G. Shtengel2, H. Hess2, C.G. Galbraith1; 1Spatial Systems Biomedicine, Oregon Health Science University, Portland, OR, 2Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, VA

11:30 am   E82    A viral fusogen hijacks the actin cytoskeleton to drive cell-cell fusion.  K. Chan1, S. Son2, E.M. Schmid2, D.A. Fletcher1,2,3,4; 1UC Berkeley/UC San Francisco Graduate Group in Bioengineering, Berkeley, CA, 2Department of Bioengineering, University of California, Berkeley, Berkeley, CA, 3Biophysics Program, University of California, Berkeley, Berkeley, CA, 4Physical Biosciences Division, Lawrence Berkeley National Laboratory, Berkeley, CA

11:40 am   E83    Firing of the harpoon-like invasion machinery of microsporidian parasites by high-speed microscopy.  P. Jaroenlak1, M. Cammer2, F. Liang2, J.J. Becnel3, D.C. Ekiert1, G. Bhabha1; 1Skirball Institute of Biomolecular Medicine, New York University School of Medicine, New York, NY, 2Microscopy Laboratory, New York University School of Medicine, New York, NY, 3Center for Medical, Agricultural, and Veterinary Entomology, Agricultural Research Service, US Department of Agriculture, Gainesville, FL

11:50 am   E84    Cell-extrinsic mechanical forces induce neutrophil polarization in the absence of leading-edge actin assembly pathways.  B.R. Graziano1, A. Diz-Muñoz2, O.D. Weiner1; 1Cardiovascular Research Institute, UCSF, San Francisco, CA, 2Cell Biology and Biophysics, EMBL, Heidelberg, Germany

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