Microsymposium 13

Molecular Mechanisms of Metabolic Reprogramming

Tuesday, December 11
11:00 am-12:00 pm
Room 29C
Moderator: Peter Yu, Ohio State University

11:00 am   E73    Cxcl12a and c-Myc promote the metabolic switch to glycolysis to support kidney repair after injury.  T.A. Yakulov1, A. Todkar1, K. Slanchev1, J. Wiegel1, A. Bona1,2,3, A. Scholz1, G. Walz1,4; 1Renal Division, University Freiburg Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany, 2Faculty of Biology, University of Freiburg, Freiburg, Germany, 3Spemann Graduate School of Biology and Medicine (SGBM), University of Freiburg, Freiburg, Germany, 4BIOSS Center for Biological Signalling Studies, University of Freiburg, Freiburg, Germany

11:10 am   E74    IGF-1’s regulates TGFβ’s profibrotic response contributing to lung fibrosis.  D.M. Hernandez1,2, M. Andrianifahanana1, X. Yin1, J. Kang1, A.H. Limper1, E.B. Leof1; 1Thoracic Disease Research Unit, Mayo Clinic College of Medicine, Rochester, MN, 2Biochemistry & Molecular Biology, Mayo Clinic Graduate School of Biomedical Sciences, Rochester, MN

11:20 am   E75    Palmitate inhibits muscle cell insulin-stimulated GLUT4 translocation and Rac1-dependent actin remodelling independently of Akt.  V. Tokarz1,2, H. Akhuanzada1,3, A. Klip1,2,3; 1Cell Biology, Hospital for Sick Children, Toronto, ON, 2Physiology, University of Toronto, Toronto, ON, 3Biochemistry, University of Toronto, Toronto, ON

11:30 am   E76    Sequential lipolysis and lipophagy pathways orchestrate lipid droplet breakdown in hepatocytes.  M.B. Schott1, S.G. Weller1, R.J. Schulze1, E.W. Krueger1, H. Cao1, C.A. Casey2,3, M.A. McNiven1; 11Department of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, MN, 2Department of Internal Medicine, University of Nebraska Medical Center, Omaha, NE, 3Research Service, Nebraska Western Iowa Health Care System, Omaha, NE

11:40 am   E77    Soluble klotho acts as a circulating FGF23 co-receptor that modifies FGF23’s receptor affinity and subsequent downstream signaling.  C. Yanucil1,2, D. Kentrup1, B. Richter1, B. Czaya1,2, I. Campos1,2, C. Faul1; 1Nephrology, University of Alabama Birmingham, Birmingham, AL, 2Cell Biology, University of Alabama Birmingham, Birmingham, AL

11:50 am   E78    Ate1 Controls Cellular Warburg Effects by modifying HIF1a with arginylation.  C. Jiang1, F. Fontanesi2, A. Barrientos2,3, T. Lampidis4, F. Zhang1; 1Molecular & Cellular Pharmacology, University of Miami Miller School of Medicine, Miami, FL, 2Biochemistry & Molecular Biology, University of Miami Miller School of Medicine, Miami, FL, 3Nurology, University of Miami Miller School of Medicine, Miami, FL, 4Cell Biology, University of Miami Miller School of Medicine, Miami, FL

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